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Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa

Multiple regulated neutrophil cell death programs contribute to host defense against infections. However, despite expressing all necessary inflammasome components, neutrophils are thought to be generally defective in Caspase-1-dependent pyroptosis. By screening different bacterial species, we found...

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Detalles Bibliográficos
Autores principales: Santoni, Karin, Pericat, David, Gorse, Leana, Buyck, Julien, Pinilla, Miriam, Prouvensier, Laure, Bagayoko, Salimata, Hessel, Audrey, Leon-Icaza, Stephen Adonai, Bellard, Elisabeth, Mazères, Serge, Doz-Deblauwe, Emilie, Winter, Nathalie, Paget, Christophe, Girard, Jean-Philippe, Pham, Christine T. N., Cougoule, Céline, Poincloux, Renaud, Lamkanfi, Mohamed, Lefrançais, Emma, Meunier, Etienne, Planès, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345480/
https://www.ncbi.nlm.nih.gov/pubmed/35849616
http://dx.doi.org/10.1371/journal.ppat.1010305