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Exercise Intervention Modulates Synaptic Plasticity by Inhibiting Excessive Microglial Activation via Exosomes

BACKGROUND: Exosomes can activate microglia to modulate neural activity and synaptic plasticity by phagocytosis of neural spines or synapses. Our previous research found that an early 4-week exercise intervention in middle cerebral artery occlusion (MCAO) rats can promote the release of exosomes and...

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Detalles Bibliográficos
Autores principales: Li, Chen, Hu, Jiayi, Liu, Wenhong, Ke, Changkai, Huang, Chuan, Bai, Yifan, Pan, Bingchen, Wang, Junyi, Wan, Chunxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345504/
https://www.ncbi.nlm.nih.gov/pubmed/35928570
http://dx.doi.org/10.3389/fncel.2022.953640