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Dapagliflozin Improves Diabetic Cardiomyopathy by Modulating the Akt/mTOR Signaling Pathway

BACKGROUND: Dapagliflozin can significantly improve heart failure, and Cx43 is one of the molecular mechanisms of heart failure. This study investigated the effect of dapagliflozin on Cx43 and Akt/mTOR signaling pathway in ventricular myocytes. METHODS: A rat model of type 2 diabetes mellitus was es...

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Detalles Bibliográficos
Autores principales: Ren, Mengxiang, Pan, Dabin, Zha, Dayong, Shan, Zeyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345717/
https://www.ncbi.nlm.nih.gov/pubmed/35928916
http://dx.doi.org/10.1155/2022/9687345