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PDGFR kinase inhibitor protects against septic death via regulation of BTLA

Sepsis, defined as life-threatening organ failure caused by a dysregulated host response to severe infection, is a major cause of death among intensive care unit patients. Therapies targeting on immunomodulatory is a new research field in sepsis treatment. B- and T-lymphocyte attenuator (BTLA) is an...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Deng, Jin, Sun, Jianhui, Zhang, Huacai, Liu, Di, Gao, Chu, Qiu, Jinchao, Liu, Wenyi, Qu, Guoxin, Wen, Dalin, Du, Juan, Zhang, Anqiang, Zeng, Ling, Jiang, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345782/
https://www.ncbi.nlm.nih.gov/pubmed/35918604
http://dx.doi.org/10.1007/s11427-021-2136-y