Homodimeric complexes of the 90–231 human prion: a multilayered computational study based on FMO/GRID-DRY approach

The molecular interaction properties and aggregation capabilities disclosed by PrP-E200K, a pathogenic mutant of the human prion protein, were investigated in detail using multilayered computational approaches. In a previous work, we reported that the electrostatic complementarity between region1 (n...

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Detalles Bibliográficos
Autores principales: Paciotti, Roberto, Storchi, Loriano, Marrone, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345805/
https://www.ncbi.nlm.nih.gov/pubmed/35918494
http://dx.doi.org/10.1007/s00894-022-05244-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345805/
https://www.ncbi.nlm.nih.gov/pubmed/35918494
http://dx.doi.org/10.1007/s00894-022-05244-2

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