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A miR-125/Sirtuin-7 pathway drives the pro-calcific potential of myeloid cells in diabetic vascular disease

AIMS/HYPOTHESIS: Ectopic calcification is a typical feature of diabetic vascular disease and resembles an accelerated ageing phenotype. We previously found an excess of myeloid calcifying cells in diabetic individuals. We herein examined molecular and cellular pathways linking atherosclerotic calcif...

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Detalles Bibliográficos
Autores principales: Vigili de Kreutzenberg, Saula, Giannella, Alessandra, Ceolotto, Giulio, Faggin, Elisabetta, Cappellari, Roberta, Mazzucato, Marta, Fraccaro, Chiara, Tarantini, Giuseppe, Avogaro, Angelo, Fadini, Gian Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345831/
https://www.ncbi.nlm.nih.gov/pubmed/35708762
http://dx.doi.org/10.1007/s00125-022-05733-2