Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation

The small intestine is a rapidly proliferating organ that is maintained by a small population of Lgr5-expressing intestinal stem cells (ISCs). However, several Lgr5-negative ISC populations have been identified, and this remarkable plasticity allows the intestine to rapidly respond to both the local...

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Detalles Bibliográficos
Autores principales: Silva, Joana, Alkan, Ferhat, Ramalho, Sofia, Snieckute, Goda, Prekovic, Stefan, Garcia, Ana Krotenberg, Hernández-Pérez, Santiago, van der Kammen, Rob, Barnum, Danielle, Hoekman, Liesbeth, Altelaar, Maarten, Zwart, Wilbert, Suijkerbuijk, Saskia Jacoba Elisabeth, Bekker-Jensen, Simon, Faller, William James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345940/
https://www.ncbi.nlm.nih.gov/pubmed/35918345
http://dx.doi.org/10.1038/s41467-022-32220-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345940/
https://www.ncbi.nlm.nih.gov/pubmed/35918345
http://dx.doi.org/10.1038/s41467-022-32220-4

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