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PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer’s disease risk

PILRA (rs1859788 A > G) has been suggested to be a protective variant for Alzheimer’s disease (AD) and is an entry co-receptor for herpes simplex virus-1. We conducted a nested case–control study of 360 1:1-matched AD subjects. Interactions between the PILRA-A allele, APOE risk variants (ε3/ε4 or...

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Detalles Bibliográficos
Autores principales: Lopatko Lindman, Karin, Jonsson, Caroline, Weidung, Bodil, Olsson, Jan, Pandey, Janardan P., Prokopenko, Dmitry, Tanzi, Rudolph E., Hallmans, Göran, Eriksson, Sture, Elgh, Fredrik, Lövheim, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346002/
https://www.ncbi.nlm.nih.gov/pubmed/35918447
http://dx.doi.org/10.1038/s41598-022-17058-6