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Multivalent protein–protein interactions are pivotal regulators of eukaryotic Hsp70 complexes
Heat shock protein 70 (Hsp70) is a molecular chaperone and central regulator of protein homeostasis (proteostasis). Paramount to this role is Hsp70’s binding to client proteins and co-chaperones to produce distinct complexes, such that understanding the protein–protein interactions (PPIs) of Hsp70 i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346034/ https://www.ncbi.nlm.nih.gov/pubmed/35670950 http://dx.doi.org/10.1007/s12192-022-01281-1 |