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Advances in UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) Covalent Inhibition

Peptidoglycan is a cross-linked polymer responsible for maintaining the bacterial cell wall integrity and morphology in Gram-negative and Gram-positive bacteria. The peptidoglycan pathway consists of the enzymatic reactions held in three steps: cytoplasmic, membrane-associated, and periplasmic. The...

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Detalles Bibliográficos
Autores principales: de Oliveira, Maycon Vinicius Damasceno, Furtado, Renan Machado, da Costa, Kauê S., Vakal, Serhii, Lima, Anderson H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346081/
https://www.ncbi.nlm.nih.gov/pubmed/35936791
http://dx.doi.org/10.3389/fmolb.2022.889825