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CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns

Respiratory syncytial virus is a leading cause of morbidity and mortality in children, due in part to their distinct immune system, characterized by impaired induction of Th 1 immunity. Here we show application of cationic adjuvant formulation CAF08, a liposomal vaccine formulation tailored to induc...

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Detalles Bibliográficos
Autores principales: van Haren, Simon D., Pedersen, Gabriel K., Kumar, Azad, Ruckwardt, Tracy J., Moin, Syed, Moore, Ian N., Minai, Mahnaz, Liu, Mark, Pak, Jensen, Borriello, Francesco, Doss-Gollin, Simon, Beijnen, Elisabeth M. S., Ahmed, Saima, Helmel, Michaela, Andersen, Peter, Graham, Barney S., Steen, Hanno, Christensen, Dennis, Levy, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346114/
https://www.ncbi.nlm.nih.gov/pubmed/35918315
http://dx.doi.org/10.1038/s41467-022-31709-2