A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors

Intracranial germ cell tumors (IGCTs) are rare brain neoplasms that mainly occur in children and adolescents with a particularly high incidence in East Asian populations. Here, we conduct a genome-wide association study (GWAS) of 133 patients with IGCTs and 762 controls of Japanese ancestry. A commo...

Descripción completa

Detalles Bibliográficos
Autores principales: Sonehara, Kyuto, Kimura, Yui, Nakano, Yoshiko, Ozawa, Tatsuya, Takahashi, Meiko, Suzuki, Ken, Fujii, Takashi, Matsushita, Yuko, Tomiyama, Arata, Kishikawa, Toshihiro, Yamamoto, Kenichi, Naito, Tatsuhiko, Suzuki, Tomonari, Yamaguchi, Shigeru, Miwa, Tomoru, Sasaki, Hikaru, Kitagawa, Masashi, Ohe, Naoyuki, Fukai, Junya, Ogiwara, Hideki, Kawamura, Atsufumi, Miyawaki, Satoru, Matsuda, Fumihiko, Kiyokawa, Nobutaka, Ichimura, Koichi, Nishikawa, Ryo, Okada, Yukinori, Terashima, Keita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346128/
https://www.ncbi.nlm.nih.gov/pubmed/35918310
http://dx.doi.org/10.1038/s41467-022-32005-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346128/
https://www.ncbi.nlm.nih.gov/pubmed/35918310
http://dx.doi.org/10.1038/s41467-022-32005-9

Ejemplares similares