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Increased systemic and adipose 11β-HSD1 activity in idiopathic intracranial hypertension

CONTEXT: Idiopathic intracranial hypertension (IIH) is a disease of raised intracranial pressure (ICP) of unknown etiology. Reductions in glucocorticoid metabolism are associated with improvements in IIH disease activity. The basal IIH glucocorticoid metabolism is yet to be assessed. OBJECTIVE: The...

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Detalles Bibliográficos
Autores principales: Westgate, Connar S J, Markey, Keira, Mitchell, James L, Yiangou, Andreas, Singhal, Rishi, Stewart, Paul, Tomlinson, Jeremy W, Lavery, Gareth G, Mollan, Susan P, Sinclair, Alexandra J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346265/
https://www.ncbi.nlm.nih.gov/pubmed/35584002
http://dx.doi.org/10.1530/EJE-22-0108