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Inhaled glucocorticoid-induced metabolome changes in asthma

OBJECTIVE: The aim of this study was toidentify dose-related systemic effects of inhaled glucocorticoids (GCs) on the global metabolome. DESIGN AND METHODS: Metabolomics/lipidomic analysis from plasma was obtained from 54 subjects receiving weekly escalating doses (µg/day) of fluticasone furoate (FF...

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Detalles Bibliográficos
Autores principales: Daley-Yates, Peter, Keppler, Brian, Brealey, Noushin, Shabbir, Shaila, Singh, Dave, Barnes, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346266/
https://www.ncbi.nlm.nih.gov/pubmed/35900313
http://dx.doi.org/10.1530/EJE-21-0912