Exosomal Vaccine Loading T Cell Epitope Peptides of SARS-CoV-2 Induces Robust CD8(+) T Cell Response in HLA-A Transgenic Mice

PURPOSE: Current vaccines for the SARS-CoV-2 virus mainly induce neutralizing antibodies but overlook the T cell responses. This study aims to generate an exosomal vaccine carrying T cell epitope peptides of SARS-CoV-2 for the induction of CD8(+) T cell response. METHODS: Thirty-one peptides present...

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Detalles Bibliográficos
Autores principales: Shen, An-Ran, Jin, Xiao-Xiao, Tang, Tao-Tao, Ding, Yan, Liu, Xiao-Tao, Zhong, Xin, Wu, Yan-Dan, Han, Xue-Lian, Zhao, Guang-Yu, Shen, Chuan-Lai, Lv, Lin-Li, Liu, Bi-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346304/
https://www.ncbi.nlm.nih.gov/pubmed/35937077
http://dx.doi.org/10.2147/IJN.S367494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346304/
https://www.ncbi.nlm.nih.gov/pubmed/35937077
http://dx.doi.org/10.2147/IJN.S367494

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