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Mechanism of Enhanced Oral Absorption of a Nano-Drug Delivery System Loaded with Trimethyl Chitosan Derivatives

INTRODUCTION: In the previous study, nanoparticles coated with trimethyl chitosan (TMC) derivatives (PPTT-NPs) could promote the oral bioavailability of panax notoginseng saponins (PNS). Herein, we chose PPTT-NPs as a model drug to study the property and mechanism of intestinal absorption in vitro a...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Lin, Shiyuan, Fang, Ruiyue, Shi, Yaling, Wu, Wei, Zhang, Wei, Chen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346306/
https://www.ncbi.nlm.nih.gov/pubmed/35937081
http://dx.doi.org/10.2147/IJN.S358832