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Phosphorylation and sulfation share a common biosynthetic pathway, but extend biochemical and evolutionary diversity of biological macromolecules in distinct ways

Phosphate and sulfate groups are integral to energy metabolism and introduce negative charges into biological macromolecules. One purpose of such modifications is to elicit precise binding/activation of protein partners. The physico-chemical properties of the two groups, while superficially similar,...

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Detalles Bibliográficos
Autores principales: Lima, M. A., Rudd, T. R., Fernig, D. G., Yates, E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346353/
https://www.ncbi.nlm.nih.gov/pubmed/35919982
http://dx.doi.org/10.1098/rsif.2022.0391