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Application of C5 inhibitors in glomerular diseases in 2021

The complement pathway is an essential mechanism in innate immunity, but it is also involved in multiple pathologies. For kidney diseases, strong evidence of a dysregulation in the alternative pathway in atypical hemolytic uremic syndrome (aHUS) led to the use of eculizumab, the first anti-C5 inhibi...

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Detalles Bibliográficos
Autores principales: Werion, Alexis, Rondeau, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Nephrology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346396/
https://www.ncbi.nlm.nih.gov/pubmed/35354244
http://dx.doi.org/10.23876/j.krcp.21.248