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Reduced symmetric dimethylation stabilizes vimentin and promotes metastasis in MTAP‐deficient lung cancer

The aggressive nature and poor prognosis of lung cancer led us to explore the mechanisms driving disease progression. Utilizing our invasive cell‐based model, we identified methylthioadenosine phosphorylase (MTAP) and confirmed its suppressive effects on tumorigenesis and metastasis. Patients with l...

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Detalles Bibliográficos
Autores principales: Chang, Wen‐Hsin, Chen, Yi‐Ju, Hsiao, Yi‐Jing, Chiang, Ching‐Cheng, Wang, Chia‐Yu, Chang, Ya‐Ling, Hong, Qi‐Sheng, Lin, Chien‐Yu, Lin, Shr‐Uen, Chang, Gee‐Chen, Chen, Hsuan‐Yu, Chen, Yu‐Ju, Chen, Ching‐Hsien, Yang, Pan‐Chyr, Yu, Sung‐Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346486/
https://www.ncbi.nlm.nih.gov/pubmed/35766227
http://dx.doi.org/10.15252/embr.202154265