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Interferon‐mediated repression of miR‐324‐5p potentiates necroptosis to facilitate antiviral defense

Mixed lineage kinase domain‐like protein (MLKL) is the terminal effector of necroptosis, a form of regulated necrosis. Optimal activation of necroptosis, which eliminates infected cells, is critical for antiviral host defense. MicroRNAs (miRNAs) regulate the expression of genes involved in various b...

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Detalles Bibliográficos
Autores principales: Dou, Xiaoyan, Yu, Xiaoliang, Du, Shujing, Han, Yu, Li, Liang, Zhang, Haoran, Yao, Ying, Du, Yayun, Wang, Xinhui, Li, Jingjing, Yang, Tao, Zhang, Wei, Yang, Chengkui, Ma, Feng, He, Sudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346494/
https://www.ncbi.nlm.nih.gov/pubmed/35735238
http://dx.doi.org/10.15252/embr.202154438