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Glutathione S-Transferase Alpha 4 Promotes Proliferation and Chemoresistance in Colorectal Cancer Cells

Glutathione S-transferase alpha 4 (GSTA4) is a phase II detoxifying enzyme that is overexpressed in colorectal cancer (CRC) and regulated by the oncogenic transcription factor AP-1. However, the role of GSTA4 in these CRC cells remains unclear. In this study, we investigated the roles of GSTA4 in th...

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Detalles Bibliográficos
Autores principales: Zhang, Zhanhu, Xu, Lili, Huang, Lin, Li, Tianqi, Wang, Jane Y., Ma, Chunhua, Bian, Xiaoyun, Ren, Xiaoyan, Li, Haibo, Wang, Xingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346510/
https://www.ncbi.nlm.nih.gov/pubmed/35936694
http://dx.doi.org/10.3389/fonc.2022.887127