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Natural history study and statistical modeling of disease progression in a preclinical model of myotubular myopathy
Generating reliable preclinical data in animal models of disease is essential in therapy development. Here, we performed statistical analysis and joint longitudinal–survival modeling of the progressive phenotype observed in Mtm1(−/y) mice, a reliable model for myotubular myopathy. Analysis of histor...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346515/ https://www.ncbi.nlm.nih.gov/pubmed/35642830 http://dx.doi.org/10.1242/dmm.049284 |