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Glutathione-depleting polymer delivering chlorin e6 for enhancing photodynamic therapy

The therapeutic effect of photodynamic therapy (PDT) is highly dependent on the intracellular production of reactive oxygen species (ROS). However, the ROS generated by photosensitizers can be consumed by the highly concentrated glutathione (GSH) in tumor cells, severely impairing the therapeutic ef...

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Detalles Bibliográficos
Autores principales: Wang, Shi-yin, Chen, Guo, Chen, Ji-feng, Wang, Jin, Deng, Shao-hui, Cheng, Du
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346557/
https://www.ncbi.nlm.nih.gov/pubmed/35975058
http://dx.doi.org/10.1039/d2ra01877b