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Effect of the array of amines on the transfection efficiency of cationic peptidomimetic lipid molecules into neural cells

The amino groups in the head group of a cationic lipid play a determinative role regarding the nucleic acid delivery efficiency of the LNP formulated from lipids. Herein, we designed four types of lipid bearing different amine-containing branched head groups to investigate the influence of type and...

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Detalles Bibliográficos
Autores principales: Yu, Xiang, Xiao, Hai, Muqier, Muqier, Han, Shuqin, Baigude, Huricha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346625/
https://www.ncbi.nlm.nih.gov/pubmed/35975061
http://dx.doi.org/10.1039/d2ra03347j