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Sulfonated red and far-red rhodamines to visualize SNAP- and Halo-tagged cell surface proteins

The (in)ability to permeate membranes is a key feature of chemical biology probes that defines their suitability for specific applications. Here we report sulfonated rhodamines that endow xanthene dyes with cellular impermeability for analysis of surface proteins. We fuse charged sulfonates to red a...

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Detalles Bibliográficos
Autores principales: Birke, Ramona, Ast, Julia, Roosen, Dorien A., Lee, Joon, Roßmann, Kilian, Huhn, Christiane, Mathes, Bettina, Lisurek, Michael, Bushiri, David, Sun, Han, Jones, Ben, Lehmann, Martin, Levitz, Joshua, Haucke, Volker, Hodson, David J., Broichhagen, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346974/
https://www.ncbi.nlm.nih.gov/pubmed/35188523
http://dx.doi.org/10.1039/d1ob02216d