Enhancement of LncRNA-HFRL expression induces cardiomyocyte inflammation, proliferation, and fibrosis via the sequestering of miR-149-5p-mediated collagen 22A inhibition

BACKGROUND: Long non-coding ribonucleic acids (lncRNAs) are believed to play crucial roles in cardiovascular diseases; however, details of the underlying mechanisms by which this occurs remain unclear. METHODS: A mouse heart failure (HF) model was established using isoproterenol (ISO), and confirmed...

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Detalles Bibliográficos
Autores principales: Li, Xiaohua, Teng, Yun, Tian, Miao, Qiu, Hailong, Zhao, Junfei, Gao, Qiang, Zhang, Yong, Zhuang, Jian, Chen, Jimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347043/
https://www.ncbi.nlm.nih.gov/pubmed/35928754
http://dx.doi.org/10.21037/atm-22-1756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347043/
https://www.ncbi.nlm.nih.gov/pubmed/35928754
http://dx.doi.org/10.21037/atm-22-1756

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