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Enhancement of LncRNA-HFRL expression induces cardiomyocyte inflammation, proliferation, and fibrosis via the sequestering of miR-149-5p-mediated collagen 22A inhibition
BACKGROUND: Long non-coding ribonucleic acids (lncRNAs) are believed to play crucial roles in cardiovascular diseases; however, details of the underlying mechanisms by which this occurs remain unclear. METHODS: A mouse heart failure (HF) model was established using isoproterenol (ISO), and confirmed...
Autores principales: | Li, Xiaohua, Teng, Yun, Tian, Miao, Qiu, Hailong, Zhao, Junfei, Gao, Qiang, Zhang, Yong, Zhuang, Jian, Chen, Jimei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347043/ https://www.ncbi.nlm.nih.gov/pubmed/35928754 http://dx.doi.org/10.21037/atm-22-1756 |
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