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The gut microbiome contributes to splenomegaly and tissue inflammation in a murine model of primary biliary cholangitis

BACKGROUND: Splenomegaly is not just a consequence of numerous chronic and acute conditions but may also contribute to their severity, due to the interaction of the spleen with the gut microbiome. This study aimed to explore the effect of the gut microbiome on splenomegaly. METHODS: We used p40(−/−)...

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Detalles Bibliográficos
Autores principales: Wang, Cheng-Bo, Wang, Yan, Yao, Yuan, Wang, Jin-Jun, Tsuneyama, Koichi, Yang, Qiong, Liu, Bin, Selmi, Carlo, Gershwin, M. Eric, Yang, Shu-Han, Lian, Zhe-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347057/
https://www.ncbi.nlm.nih.gov/pubmed/35928756
http://dx.doi.org/10.21037/atm-21-5448