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Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration

BACKGROUND: Intervertebral disc (IVD) is a highly rhythmic tissue, which experiences a diurnal cycle of high/low mechanical loading via the changes of activity/rest phase. There are signs that disruption of the peripheral IVD clock is related to the process of intervertebral disc degeneration (IDD)....

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Detalles Bibliográficos
Autores principales: Peng, Pandi, Wang, Dong, Xu, Xiaolong, Wang, Di, Gao, Bo, Wang, Han, Jia, Haoruo, Shang, Qiliang, Zheng, Chao, Gao, Chu, Mao, Jianxin, Luo, Zhuojing, Yang, Liu, Hu, Xueyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347076/
https://www.ncbi.nlm.nih.gov/pubmed/35922862
http://dx.doi.org/10.1186/s13075-022-02876-w