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Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration
BACKGROUND: Intervertebral disc (IVD) is a highly rhythmic tissue, which experiences a diurnal cycle of high/low mechanical loading via the changes of activity/rest phase. There are signs that disruption of the peripheral IVD clock is related to the process of intervertebral disc degeneration (IDD)....
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347076/ https://www.ncbi.nlm.nih.gov/pubmed/35922862 http://dx.doi.org/10.1186/s13075-022-02876-w |