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Secreted heat shock protein gp96-Ig and OX40L-Fc combination vaccine enhances SARS-CoV-2 Spike (S) protein-specific B and T cell immune responses

Encouraging protection results from current mRNA-based SARS-CoV-2 vaccine platforms are primarily due to the induction of SARS- CoV-2- specific B cell antibody and CD4 + T cell. Even though, current mRNA vaccine platforms are adept in inducing SARS-CoV2-specific CD8 + T cell, much less is known abou...

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Detalles Bibliográficos
Autores principales: Padula, Laura, Fisher, Eva, Rivas, Katelyn, Podack, Kristin, Frasca, Daniela, Kupritz, Jonah, Seavey, Matthew M., Jayaraman, Padmini, Dixon, Eric, Jasuja, Rahul, Strbo, Natasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347141/
https://www.ncbi.nlm.nih.gov/pubmed/35936992
http://dx.doi.org/10.1016/j.jvacx.2022.100202