Germline variants profiling of BRCA1 and BRCA2 in Chinese Hakka breast and ovarian cancer patients

OBJECTIVE: To investigate the prevalence and spectrum of BRCA1 and BRCA2 mutations in Chinese Hakka patients with breast and ovarian cancer. METHODS: A total of 1,664 breast or ovarian cancer patients were enrolled for genetic testing at our hospital. Germline mutations of the BRCA gene were analyse...

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Detalles Bibliográficos
Autores principales: Zhang, Yunuo, Wu, Heming, Yu, Zhikang, Li, Liang, Zhang, Jinhong, Liang, Xinhong, Huang, Qingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347172/
https://www.ncbi.nlm.nih.gov/pubmed/35918668
http://dx.doi.org/10.1186/s12885-022-09943-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347172/
https://www.ncbi.nlm.nih.gov/pubmed/35918668
http://dx.doi.org/10.1186/s12885-022-09943-0

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