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Activation of the sigma-1 receptor exerts cardioprotection in a rodent model of chronic heart failure by stimulation of angiogenesis

BACKGROUND: Angiogenesis plays a critical role on post-infarction heart failure (PIHF), the presence of which facilitates additional blood supply to maintain the survival of residual cardiomyocytes. The sigma-1 receptor (S1R) has been substantiated to stimulate angiogenesis, with the effect on a mod...

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Detalles Bibliográficos
Autores principales: Zhao, Xin, Liu, Xin, Chen, Xiuhuan, Han, Xueyu, Sun, Yazhou, Fo, Yuhong, Wang, Xiukun, Qu, Chuan, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347174/
https://www.ncbi.nlm.nih.gov/pubmed/35922746
http://dx.doi.org/10.1186/s10020-022-00517-1