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Pharmacological activation of the hERG K(+) channel for the management of the long QT syndrome: A review

In the human heart, the rapid delayed rectifier K(+) current (I (Kr)) contributes significantly to ventricular action potential (AP) repolarization and to set the duration of the QT interval of the surface electrocardiogram (ECG). The pore‐forming (α) subunit of the I (Kr) channel is encoded by KCNH...

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Detalles Bibliográficos
Autores principales: El Harchi, Aziza, Brincourt, Oriane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347208/
https://www.ncbi.nlm.nih.gov/pubmed/35936037
http://dx.doi.org/10.1002/joa3.12741