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Inhibitors of Gq signalling down-regulate β-catenin expression & function in human colon cancer cells

BACKGROUND & OBJECTIVES: β-catenin signalling plays a key role in maintaining normal cellular physiology, and therefore, its deregulation can lead to many human diseases including cancers. Previously, we have shown that the activation of Gq signalling positively regulates β-catenin by inhibiting...

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Detalles Bibliográficos
Autores principales: Forghani, Nasim, Najafi, S. Mahmoud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347257/
https://www.ncbi.nlm.nih.gov/pubmed/35662088
http://dx.doi.org/10.4103/ijmr.IJMR_1370_19