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Confirmation of Decreased Rates of Cerebral Protein Synthesis In Vivo in a Mouse Model of Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that results in intellectual disability and, in ∼50% of patients, autism spectrum disorder. The protein products that are altered in TSC (TSC1 and TSC2) form a complex to inhibit the mammalian target of rapamycin [mTOR; mTOR complex...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347307/ https://www.ncbi.nlm.nih.gov/pubmed/35851298 http://dx.doi.org/10.1523/ENEURO.0480-21.2022 |