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Confirmation of Decreased Rates of Cerebral Protein Synthesis In Vivo in a Mouse Model of Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that results in intellectual disability and, in ∼50% of patients, autism spectrum disorder. The protein products that are altered in TSC (TSC1 and TSC2) form a complex to inhibit the mammalian target of rapamycin [mTOR; mTOR complex...

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Detalles Bibliográficos
Autores principales: Saré, Rachel Michelle, Torossian, Anita, Loutaev, Inna, Smith, Carolyn Beebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347307/
https://www.ncbi.nlm.nih.gov/pubmed/35851298
http://dx.doi.org/10.1523/ENEURO.0480-21.2022

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