Hydrophobic cavity-directed azide-acetyllysine photochemistry for profiling non-histone interacting partners of bromodomain protein 1

Bromodomain containing protein 1 (BRD1) plays critical roles in chromatin acetylation, gene transcription, erythropoiesis, and brain development. BRD1 is also implicated in several human conditions and is a therapeutic target for cancer. Although, the bromodomain is known to bind acetylated histones...

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Detalles Bibliográficos
Autores principales: Kuwik, Jordan, Wagner, Shana, Sudhamalla, Babu, Debiec, Ronald, Islam, Kabirul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347360/
https://www.ncbi.nlm.nih.gov/pubmed/35975005
http://dx.doi.org/10.1039/d2cb00043a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347360/
https://www.ncbi.nlm.nih.gov/pubmed/35975005
http://dx.doi.org/10.1039/d2cb00043a

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