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Hydrophobic cavity-directed azide-acetyllysine photochemistry for profiling non-histone interacting partners of bromodomain protein 1
Bromodomain containing protein 1 (BRD1) plays critical roles in chromatin acetylation, gene transcription, erythropoiesis, and brain development. BRD1 is also implicated in several human conditions and is a therapeutic target for cancer. Although, the bromodomain is known to bind acetylated histones...
Autores principales: | Kuwik, Jordan, Wagner, Shana, Sudhamalla, Babu, Debiec, Ronald, Islam, Kabirul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347360/ https://www.ncbi.nlm.nih.gov/pubmed/35975005 http://dx.doi.org/10.1039/d2cb00043a |
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