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A Modified Arrestin1 Increases Lactate Production in the Retina and Slows Retinal Degeneration

Glucose metabolism in the retina is carefully orchestrated, with glucose being delivered to photoreceptors from the choroidal circulation through the retinal pigmented epithelium (RPE). In photoreceptors, glucose is processed principally by aerobic glycolysis, from which the lactate byproduct is pro...

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Detalles Bibliográficos
Autores principales: Nelson, Tiffany S., Simpson, Chiab, Dyka, Frank, Dinculescu, Astra, Smith, W. Clay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347377/
https://www.ncbi.nlm.nih.gov/pubmed/35081746
http://dx.doi.org/10.1089/hum.2021.272