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Advanced Age and Neurotrauma Diminish Glutathione and Impair Antioxidant Defense after Spinal Cord Injury

Advanced age at the time of spinal cord injury (SCI) exacerbates damage from reactive oxygen species (ROS). Mechanisms underlying this age-dependent response are not well understood and may arise from decreased antioxidant defense. We investigated how spinal cord levels of the antioxidant glutathion...

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Detalles Bibliográficos
Autores principales: Stewart, Andrew N., Glaser, Ethan P., Mott, Caitlin A., Bailey, William M., Sullivan, Patrick G., Patel, Samir P., Gensel, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347421/
https://www.ncbi.nlm.nih.gov/pubmed/35373589
http://dx.doi.org/10.1089/neu.2022.0010