Production of novel SARS‐CoV‐2 Spike truncations in Chinese hamster ovary cells leads to high expression and binding to antibodies

SARS‐CoV‐2 Spike is a key protein that mediates viral entry into cells and elicits antibody responses. Its importance in infection, diagnostics, and vaccinations has created a large demand for purified Spike for clinical and research applications. Spike is difficult to express, prompting modificatio...

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Detalles Bibliográficos
Autores principales: Minami, Shiaki A., Jung, Seongwon, Huang, Yihan, Harris, Bradley S., Kenaston, Matthew W., Faller, Roland, Nandi, Somen, McDonald, Karen A., Shah, Priya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347691/
https://www.ncbi.nlm.nih.gov/pubmed/35657481
http://dx.doi.org/10.1002/biot.202100678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347691/
https://www.ncbi.nlm.nih.gov/pubmed/35657481
http://dx.doi.org/10.1002/biot.202100678

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