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Production of novel SARS‐CoV‐2 Spike truncations in Chinese hamster ovary cells leads to high expression and binding to antibodies
SARS‐CoV‐2 Spike is a key protein that mediates viral entry into cells and elicits antibody responses. Its importance in infection, diagnostics, and vaccinations has created a large demand for purified Spike for clinical and research applications. Spike is difficult to express, prompting modificatio...
Autores principales: | Minami, Shiaki A., Jung, Seongwon, Huang, Yihan, Harris, Bradley S., Kenaston, Matthew W., Faller, Roland, Nandi, Somen, McDonald, Karen A., Shah, Priya S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347691/ https://www.ncbi.nlm.nih.gov/pubmed/35657481 http://dx.doi.org/10.1002/biot.202100678 |
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