Selective reaction monitoring approach using structure-defined synthetic glycopeptides for validating glycopeptide biomarkers pre-determined by bottom-up glycoproteomics

Clusterin is a heavily glycosylated protein that is upregulated in various cancer and neurological diseases. The findings by the Hancock and Iliopoulos group that levels of the tryptic glycopeptide derived from plasma clusterin, (372)Leu-Ala-Asn-Leu-Thr-Gln-Gly-Glu-Asp-Gln-Tyr-Tyr-Leu-Arg(385) with...

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Detalles Bibliográficos
Autores principales: Shiratori, Kouta, Yokoi, Yasuhiro, Wakui, Hajime, Hirane, Nozomi, Otaki, Michiru, Hinou, Hiroshi, Yoneyama, Tohru, Hatakeyama, Shingo, Kimura, Satoshi, Ohyama, Chikara, Nishimura, Shin-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347767/
https://www.ncbi.nlm.nih.gov/pubmed/35975084
http://dx.doi.org/10.1039/d2ra02903k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347767/
https://www.ncbi.nlm.nih.gov/pubmed/35975084
http://dx.doi.org/10.1039/d2ra02903k

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