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Selective reaction monitoring approach using structure-defined synthetic glycopeptides for validating glycopeptide biomarkers pre-determined by bottom-up glycoproteomics
Clusterin is a heavily glycosylated protein that is upregulated in various cancer and neurological diseases. The findings by the Hancock and Iliopoulos group that levels of the tryptic glycopeptide derived from plasma clusterin, (372)Leu-Ala-Asn-Leu-Thr-Gln-Gly-Glu-Asp-Gln-Tyr-Tyr-Leu-Arg(385) with...
Autores principales: | Shiratori, Kouta, Yokoi, Yasuhiro, Wakui, Hajime, Hirane, Nozomi, Otaki, Michiru, Hinou, Hiroshi, Yoneyama, Tohru, Hatakeyama, Shingo, Kimura, Satoshi, Ohyama, Chikara, Nishimura, Shin-Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347767/ https://www.ncbi.nlm.nih.gov/pubmed/35975084 http://dx.doi.org/10.1039/d2ra02903k |
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