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(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H(2)O(2) Through Activation of Nrf2 Pathway

Background: Oxidative stress is associated with the pathogenesis of ischemic stroke (±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) benzoate (BFB) is a novel compound modified by dl-3-n-butylphthalide (NBP). Here, we hypothesized that BFB may protect the PC12 cells against H(2)O(2)-induced oxidative stress i...

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Detalles Bibliográficos
Autores principales: Qi, Saidan, Zhang, Xiaojiao, Fu, Zhenzhen, Pi, Anran, Shi, Feiyan, Fan, Yanan, Zhang, Jiahua, Xiao, Tingting, Shang, Dong, Lin, Meng, Gao, Na, Chang, Junbiao, Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348035/
https://www.ncbi.nlm.nih.gov/pubmed/35935850
http://dx.doi.org/10.3389/fphar.2022.943111