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In silico analysis of mutations near S1/S2 cleavage site in SARS‐CoV‐2 spike protein reveals increased propensity of glycosylation in Omicron strain

Cleavage of the severe respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) spike protein has been demonstrated to contribute to viral‐cell fusion and syncytia formation. Studies have shown that variants of concern (VOC) and variants of interest (VOI) show differing membrane fusion capacity. Mutations ne...

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Detalles Bibliográficos
Autores principales: Beaudoin, Christopher A., Pandurangan, Arun P., Kim, So Yeon, Hamaia, Samir W., Huang, Christopher L.‐H., Blundell, Tom L., Vedithi, Sundeep Chaitanya, Jackson, Antony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348480/
https://www.ncbi.nlm.nih.gov/pubmed/35575289
http://dx.doi.org/10.1002/jmv.27845