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Preparation and Cytotoxic Evaluation of PGV-1 Derivative, CCA-1.1, as a New Curcumin Analog with Improved-Physicochemical and Pharmacological Properties

Purpose: This study aimed to challenge the anticancer potency of pentagamavunone-1 (PGV- 1) and obtain a new compound (Chemoprevention-Curcumin Analog 1.1, CCA-1.1) with improved chemical and pharmacological properties. Methods: CCA-1.1 was prepared by changing the ketone group of PGV-1 into a hydro...

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Detalles Bibliográficos
Autores principales: Utomo, Rohmad Yudi, Wulandari, Febri, Novitasari, Dhania, Lestari, Beni, Susidarti, Ratna Asmah, Jenie, Riris Istighfari, Kato, Jun-ya, Sardjiman, Sardjiman, Meiyanto, Edy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348534/
https://www.ncbi.nlm.nih.gov/pubmed/35935043
http://dx.doi.org/10.34172/apb.2022.063