Sclareol Inhibits Hypoxia-Inducible Factor-1α Accumulation and Induces Apoptosis in Hypoxic Cancer Cells

Purpose: The hypoxia in solid tumors is associated with the resistance to chemo/radiotherapy. Hypoxia-inducible factor-1 (HIF-1) plays a key role in cell remodeling to hypoxia. Therefore, the inhibition of HIF-1 accumulation is considered a hopeful strategy for the treatment of cancer. Here, we aime...

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Detalles Bibliográficos
Autores principales: Vandghanooni, Somayeh, Farajzadeh Vahid, Zahra, Nakhlband, Ailar, Bahadori, Mir Babak, Eskandani, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348540/
https://www.ncbi.nlm.nih.gov/pubmed/35935045
http://dx.doi.org/10.34172/apb.2022.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348540/
https://www.ncbi.nlm.nih.gov/pubmed/35935045
http://dx.doi.org/10.34172/apb.2022.062

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