RFWD3 and translesion DNA polymerases contribute to PCNA modification–dependent DNA damage tolerance

DNA damage tolerance pathways are regulated by proliferating cell nuclear antigen (PCNA) modifications at lysine 164. Translesion DNA synthesis by DNA polymerase η (Polη) is well studied, but less is known about Polη-independent mechanisms. Illudin S and its derivatives induce alkyl DNA adducts, whi...

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Detalles Bibliográficos
Autores principales: Kanao, Rie, Kawai, Hidehiko, Taniguchi, Toshiyasu, Takata, Minoru, Masutani, Chikahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348633/
https://www.ncbi.nlm.nih.gov/pubmed/35905994
http://dx.doi.org/10.26508/lsa.202201584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348633/
https://www.ncbi.nlm.nih.gov/pubmed/35905994
http://dx.doi.org/10.26508/lsa.202201584

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