Cargando…
Insight into the mechanism of DNA synthesis by human terminal deoxynucleotidyltransferase
Terminal deoxynucleotidyltransferase (TdT) is a member of the DNA polymerase X family that is responsible for random addition of nucleotides to single-stranded DNA. We present investigation into the role of metal ions and specific interactions of dNTP with active-site amino acid residues in the mech...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348634/ https://www.ncbi.nlm.nih.gov/pubmed/35914812 http://dx.doi.org/10.26508/lsa.202201428 |